The 5 Best Digestive Enzymes, According To Dietitians

Nikhil Goswami

When your body is in good working order, digestive enzymes are produced naturally to aid digestion by breaking down and absorbing nutrients. The pancreas spontaneously produces these digestive enzymes amylases for carbohydrates, lipases for fats, and proteins.

Probiotics may be included in digestive enzyme supplements to assist in enhancing the function of your gut flora, which is the bacteria that dwell in your digestive system and play an important role in your overall health. 

In this post, you’ll learn about the five best digestive enzymes to use, how they function, Also, what to look for when buying digestive enzymes.

Top 5 Picks For The Best Digestive Enzymes

  1. Pure Encapsulations Digestive Enzymes – Overall Best Digestive Enzymes, Editor’s Choice
  2. Vital Plan Active Enzymes – Top Rated Digestive Pills By Users
  3. NutraOne Vitality Powder – Most Popular Digestive Supplements
  4. Sunwarrior Enzorb – Highly Recommended Digestive Enzyme Supplements & Vitamins For Bloating
  5. Global Healing VeganZymes – Best Prime Choice For  Supplements for Gut Health

#1. Pure Encapsulations Digestive Enzymes – Overall Best Digestive Enzymes, Editor’s Choice


Digestive Enzymes Ultra by Pure Encapsulations has 13 distinct enzymes that tackle all of the most frequent causes of digestive problems. The enzymes supplied in the supplement targets dairy, fiber, lipids, carbs, and proteins. Only the “extras” included in the greatest digestive enzyme supplements are missing: vitamins, minerals, and probiotic bacteria cultures to help the body’s natural digestive skills over time.

Digestive Enzymes Ultra from Pure Encapsulations contains 391 mg of the proprietary enzyme blend, comprising 13 digestive enzymes like protease, lipase, and amylase. This high-quality digestive enzyme is devoid of wheat, gluten, egg, peanuts, magnesium stearate, hydrogenated oil, artificial sweeteners and colors, and other unnecessary excipients, as are all Pure Encapsulations products.

It’s vital to remember that everyone’s results will vary while taking a new product like Pure Encapsulations Digestive Enzymes Ultra. To get the greatest benefits with Pure Encapsulations Digestive Enzymes Ultra, read the directions carefully and remember that everyone’s body and digestive system are unique.

With that in mind, unless you also make dietary adjustments, the benefits of using Pure Encapsulations Digestive Enzymes Ultra will vary. Only then will results and relief from gas, gluten sensitivity, IBS, lactose intolerance, bloating, diarrhea, and constipation be seen.


  • Gas, gluten intolerance, lactose intolerance, bloating, diarrhea, and constipation are all problems that Pure Encapsulations Digestive Enzymes Ultra is reported to help with. It claims to alleviate symptoms associated with poor food digestion. Although the effects of this supplement are difficult to believe, their ingredient list has been demonstrated to have some form of influence on digestive difficulties.
  • Pure Encapsulations Digestive Enzymes Ultra’s stand-alone components are safe in small doses of dietary supplementation. There are no substances in Pure Encapsulations Digestive Enzymes Ultra documented to pose a health risk.


  • This mixture was created using only premium-quality ingredients
  • FDA-approved and GMP-compliant
  • Boost your bowel motions
  • Allow you to eat whatever you want
  • Help Digest the complex proteins, lipids, and carbs
  • Boost your energy levels while
  • The supplement also assists in the regulation of digestive hormone output


  • The first few times may result in gas and bloating

Customer Experience

Only a few essential ingredients are included in Pure Encapsulations Digestive Enzymes Ultra by the manufacturer. On the other hand, the producer should go into greater detail on the ingredients of the product. Instead of just stating that the product is rated #1, it would be helpful for the site to present more evidence of clinical research, especially as this supplement is among the most expensive options available when considering the dosage and time frame during which it must be taken.

People of all ages with digestive problems, such as gas, gluten intolerance, irritable bowel syndrome, lactose intolerance, bloating, diarrhea, and constipation, are suffering more than ever. A good digestive health supplement should have elements that have been clinically proven to relieve digestive problems and prevent them from recurring.

⇒Visit the official website of Pure Encapsulations Digestive Enzymes

#2. Vital Plan Active Enzymes -Top Rated Digestive Pills By Users


In comparison to other digestive products, Vital Plan’s Active Enzymes include 470 mg of enzymes per serving and are made with 15 plant-based digestive enzymes. Cardamom and fennel seeds are among the new additions. These digestive enzymes help break down food and absorb nutrients, so they’re beneficial for overall health. Developed under the guidance of a doctor and derived from plants, these capsules support healthy digestion.

A comprehensive spectrum of digestive enzymes is included in Vital Plan’s Active Enzymes Supplement to help with occasional excess gas, bloating, and irregularity. Unique formulations of Amylase, Alpha Galactosidase, Protease, Lipase, Bromelain, and other time-tested plant-based enzymes are used in Active Enzymes. They are also available in other forms.

It replaces the body’s supply of digestive enzymes essential for maintaining a healthy microbiome, breaking down meals properly, and preventing the growth of pathogenic microorganisms that feed on leftovers. Cardamom and fennel help calm GI tract muscles and reduce bloating, gas, and intestinal spasms, while advanced enzymes assist proper GI tract movement, digestion, and absorption.

The Active Enzymes Supplement from Vital Plan comprises a variety of enzymes derived from plants that help indigestion. This product was created with bloating, constipation, indigestion, and gas as primary goals. Supplements like these make sure you’re getting enough of the essential nutrients your body needs to stay healthy.


  • Incorporating a prebiotic and probiotic blend into your diet can help with digestion and absorption of nutrients. It also has a mixture of ten enzymes from plants, including Amylase, Glucoamylase, Lipase, Protease, Invertase, Maltase, Cellulase, Bromelain, Lactase, and Papain, among others. There are anti-bloating properties in both turmeric and green papaya that make them a great option.
  • Vital Plan’s Active Enzymes Supplement provides a comprehensive and strong enzyme array for optimal digestion and absorption of all foods and nutrients. This plant-based solution utilizes every enzyme to its full potential.


  • Lower the level of inflammation
  • Reduce the number of times you get diarrhea
  • Long-term healthy gut bacteria for better gut health
  • Enhance the bowel system
  • Restore blood flow by any means necessary
  • Dairy, soy, and egg-free
  • How to deal with problems with the gallbladder
  • Maintain a healthy glow on your face
  • Stop stomach aches in their tracks


  • Capsules made of gelatin are not suitable for vegans

Customer Experience

Dr. Rawls conducts clinical-grade ingredient research and formulation for Vital Plan products, subjected to 169-point independent testing. In addition to their certificates of analysis and transparent labeling, they sell only products they would eat or drink.

With this startup, they hope to change the way consumers see supplements in a sector full of dubious players. They’re ecstatic to be one of the first dietary supplements firms to be approved as a B Corp. To them, it’s all about bringing the power of nature and wellness to life for their consumers.

⇒Visit the official website of Vital Plan Active Enzymes

#3. NutraOne Vitality Powder – Most Popular Digestive Supplements


Vitamin and micronutrient supplements like Vitality Powder give your body what it needs to function properly and perform at its best. To keep you active, Vitality is a multivitamin powder made with the best cold-pressed vitamins and minerals. When you’re feeling stressed or sick, take an additional serving of 1 scoop in 8-12 ounces of water.

This powder boosts natural energy by turning food into usable energy, reducing tension, and promoting restful sleep. This supplement contains antioxidants and vitamins to combat infection and cell damage while increasing collagen formation to keep arteries healthy and keep cartilage, bones, and teeth in good condition to strengthen the body’s immune system.

A safe and effective multivitamin powder supplement made in the United States with good manufacturing practices and naturally occurring digestive enzymes. This low-sugar multivitamin powder is flavored naturally and sweetened with stevia. It aids in blood sugar regulation and promotes the proper metabolism of carbs, proteins, and lipids.


  • With NutraOne Vitality Powder, you get enzymes, probiotic bacteria, and the nutrients required to grow. This is a huge advantage. Resetting your gastrointestinal bacteria population in this manner allows you to absorb nutrients better while also repopulating your system with bacteria and enzymes that are better suited for digestion and absorption of your meal.
  • Even if that’s all you’re after, NutraOne Vitality Powder may not be the best choice because it lacks cellulose and other digestive enzymes that break down dietary fiber slowly and reduce gas production. This is a common problem for people with digestive issues, so you may struggle to find success with NutraOne Vitality Powder.


  • Dairy, soy, and egg-free
  • Support for gallbladder problems
  • Keep your skin in good shape
  • Get rid of stomach aches
  • Ingredients of the highest quality
  • FDA-approved and GMP-compliant


  • It is gluten-free
  • The first few times, you’ll get bloated

Customer Experience

NutraOne Vitality Powder is one of our favorites since it contains a digestive enzyme blend of amylase, protease, and cellulose, as well as a full multivitamin. One serving of powder contains more than your daily dosage of vitamins A, C, D, and B12, as well as digestive enzymes that can speed up your metabolism and help you get more energy from your food.

⇒Visit the official website of NutraOne Vitality Powder

#4. Sunwarrior Enzorb – Highly Recommended Digestive Enzyme Supplements & Vitamins For Bloating


Sunwarrior Enzorb digestive improvement enzymes provide a wide range of enzymes for improved digestion and absorption of a wide range of meals and nutrients. Each enzyme has a specialized role, and none of them go to waste in our plant-based recipe.

Enhancement of Digestion Enzymes concentrates on enzyme quality, pH range, and a broad range of enzymes. Vegans will be pleased to learn that Sunwarrior Enzorb’s composition contains 15 plant-based enzymes, making it ideal for them.

Ingredients present in each serving of four capsules:

  • Proteases
  • Amylase
  • Fatty Acids-stable protease
  • Glucoamylase
  • Cellulase
  • Peptidase
  • Lactase
  • Lipase
  • Alpha-galactosidase
  • Pectinase
  • Bromelain
  • Papain
  • Hemicellulose
  • Invertase
  • Xylanase

Hydrochloric acid is also present, which aids in absorbing several critical minerals such as folate, vitamin B12, ascorbic acid, fatty acids, beta-carotene, iron, and various types of calcium, magnesium, and zinc.


  • Sunwarrior Enzorb contains 15 different enzymes that assist your body in processing all of the most common types of foods that cause digestive troubles, plus herbal extracts like ginger, fennel seed, and turmeric help you absorb nutrients more effectively.


  • Aids in the digestion of difficult-to-digest protiens & carbohydrates present in legumes
  • Vegan and vegetarian friendly
  • Packaging that can be recycled


  • Four capsules make a serving

Customer Experience

This digestive enzyme product is vegetarian, gluten-free, non-dairy, and soy-free, with a plant-based formula popular with vegan-loving customers. It contains AstraZyme, a patented blend of enzymes, extracts, and minerals that aid in the breakdown and absorption of the nutrients your body requires to repair damage and perform at its best. We like that it has a wide spectrum of enzymes and is free of animal-derived ingredients.

⇒ Visit the official website of Sunwarrior Enzorb

#5. Global Healing VeganZymes – Best Prime Choice For  Supplements for Gut Health


VeganZyme by Global Healing is number five on our list of the finest digestive enzymes. You get roughly 1000mg of enzymes per meal from a combination of 20 vegan enzymes. Organic gum acacia, organic rice hulls, and the vegetable capsule are also included in this Global Healing formula.

This finest digestive enzyme supplement is made to help with digestion and immune system support. This product is one of our favorites since it has a strong blend of 20 different digestive enzymes. As a reason, you can be confident in your decision to use this brand.


  • VeganZyme aids digestion by converting food into micronutrients that your body can utilize and absorb, and digestion runs smoothly when enzyme levels are healthy.
  • VeganZyme, a broad-spectrum enzyme supplement, helps the body digest the foods that upset your stomach, whether you experience gas and bloating sometimes or regularly.


  • Helps with foods that are hot, raw, or processed
  • Help you with gas and bloating
  • It consists of both pre and probiotic ingredients


  • Produced in a factory that also processes gluten

Customer Experience

Global Healing’s VeganZyme pill is popular with customers because it contains a strong mix of vegan digestive enzymes derived solely from plants. As well as aiding digestion, this nutritional supplement also works to strengthen your immune system and improve your general well-being. You can feel good about using this digestive enzyme supplement because it has no ingredients produced from animals, including the capsule, which is vegan.

⇒Visit the official website of Global Healing VeganZymes

Buying Guide: Factors To Consider Before Choosing The Digestive Enzymes 

Here are the factors we used to pick the best digestive enzyme products to suggest.

  • Full-Spectrum

We looked for digestive enzyme supplements with multiple enzymes that could aid in the digestion of various nutrients. “Full-spectrum” or “wide spectrum” enzymes are terms used to describe these enzymes.

  • Plant-Based

Instead of food enzymes, we chose brands that use plant-based enzymes. These are not only a more environmentally friendly solution, but they are also easier and more effective for your body than plant-based protein powders.

  • Added Ingredients

We evaluated the other ingredients and vitamins added to any digestive enzyme supplements on our list to ensure they weren’t just fillers and could genuinely help with better digestion.

  • Research

Clinical studies and third-party lab tests back up the best digestive enzymes for good health. Supplements created by a doctor or nutritionist are also highlighted.

Benefits of Digestive Enzymes

  • Help Digest Food Better

Digestive enzyme supplements are enzymes generated from plants and microbes that works to digest proteins, carbs, and fats. They maintain the health of your gastrointestinal system and aid in the treatment of a variety of digestive diseases.

  • Boost Nutrient Absorption

Digestive enzyme supplements help you absorb more nutrients from your meals by breaking down proteins, lipids, and carbs. Nutrients are transferred from the small intestine to the bloodstream.

Fats, carbohydrates, and proteins are broken down into smaller molecules by enzymes, absorbing them more easily. Your immunity will also benefit from this.

  • Reduce Bloating And Gas

Complex carbohydrates are broken down by enzymes like alpha-galactosidase and cellulases like soybeans, veggies, and grains. Because these foods are tough to digest, problems like gas, bloating, and stomach pain are lessened when enzymes assist break them down.

Lipase and lactase, for example, aid in the digestion of fiber-rich vegetables, dairy products, and legumes. Digestive enzyme supplements may be helpful if you suffer any discomfort after eating these foods.

  • Help Digest Dairy

Lactose intolerance affects over 68 percent of the world’s population. Lactase is a crucial enzyme that many people lack. Lactase is the main enzyme that helps absorb lactose, a sugar present in milk, ice cream, butter, and other dairy items. Lactase-containing digestive enzyme supplements can help alleviate the symptoms of poor dairy digestion.

  • Reduce Gastrointestinal Disorders

Ninety-eight persons with Functional Gastrointestinal Disorders were requested to consume probiotics and digestive enzymes for eight weeks as part of a study experiment on Functional Gastrointestinal digestive disorders at the Atlanta Center For Holistic And Integrative Medicine.

According to the findings, the individuals’ gastrointestinal quality of life scores improved, and they lost a substantial amount of weight.

  • Reduce Acid Reflux

Acid reflux is a digestive ailment that affects the lower esophageal sphincter, often known as gastroesophageal reflux disease. In other words, the contents of the stomach reflux into the esophagus, resulting in heartburn. When combined with a change in lifestyle and food, Digestive enzyme supplements can assist in reversing the disease. These supplements help to empty your stomach and minimize stomach amino acids reflux.

  • May Help Manage Irritable Bowel Disease

Gastrointestinal Issues damage the stomach. Constipation and bloating are side effects. Digestive enzyme supplements can help alleviate IBS symptoms by breaking down complex carbohydrates, proteins, and lipids. Lactobacilli and probiotics, which aid digestion, are included in these supplements.

  • May Give You Clearer Skin

A healthy digestive system is linked to several physiological processes. Digestive systems include your skin as well. The digestive system can notice the result of your body’s inability to absorb necessary nutrients on your skin. You may get breakouts, and acne if you have a lot of inflammation in your system.

Precautions That You Should Take For Digestive Enzymes

  • Digestive enzyme supplements only work if you’re eating something. It is not recommended to take them on an empty stomach.
  • These vitamins are designed to help your body deal with digestive issues. Your body will continue to generate the essential digestive enzymes on its own once it has healed. Unfortunately, it can take several months for your digestion to return to normal. As a result, taking these supplements may be beneficial.
  • Different brands recommend various dosages. Some digestive supplements should be taken with food, while people should take others before eating. Before you use it, double-check the directions on the label.
  • The adverse effects are minimal because digestive enzyme supplements are derived from plants. However, they can trigger moderate allergic reactions to a specific enzyme in some people, resulting in constant diarrhea, nausea, or stomach cramps.
  • Examine the label carefully to check whether there are any ingredients to which you are allergic. Consult a doctor right away if you’re having irritation or heartburn.

What To Look for When Choosing Digestive Enzyme Supplements?

With many products on the marketplace promising to be the greatest digestive enzymes supplement, finding one right for you can be tough. Finding one right for you can be tough.

We recommend researching the enzyme support they provide and trying out a couple of the digestive enzyme supplements listed above to see which one you like. Please make sure any digestive enzyme supplement you buy is of good quality before you buy it.

  • Types Of Enzyme

The number and type of digestive enzymes are included among the essential features to consider in any digestive enzymes supplement. The supplement is the number and type of digestive enzymes included. If your system has problems breaking anything, ensure an enzyme that can help you break it down is provided. Ensure an enzyme that can help you break it down is provided.

For instance, having protease to assist digest proteins, digestive enzyme lipase to help break down fats, and amylase to help break down proteins & carbohydrates is excellent. Consider having at least three types of digestive enzymes when seeking the best digestive enzymes.

  • Source

Some digestive enzyme supplements are made with plant-based ingredients; some enzymes are made with animal-based ingredients. Make sure you’re buying a plant-based supplement if you don’t eat animal products. If you’re willing to experiment, try both types and see if you can tell the difference. Both can help you locate the best digestive enzymes for different reasons.

Pay attention to the number of chemicals and hormones utilized in the digestive enzyme supplement extraction procedure. It’s important to take a supplement that’s non-GMO and scientifically proven. As a result, doctors and nutritionists indeed create the majority of the greatest digestive enzyme supplements.

  • Customer Reviews

Speaking with someone who has used a product is one of the best methods to determine whether it works or not. Look at the company’s website for customer reviews to see what people are saying. What do they enjoy doing? What is it that they dislike?

  • Active Ingredients

There are a variety of specialized digestive enzymes available to meet whatever deficiencies your system may have. If dairy is causing you problems, a lactase supplement should be your first line of defense.

Different digestive enzymes and their functions are very straightforward to detect. Proteases, for example, degrade proteins, lipases degrade lipids (or dietary fat), and amylases degrade carbohydrates.

  • Usage

IBS, celiac disease, and ulcerative colitis are among the most prevalent conditions for prescribed digestive enzymes. You’ll want to hunt for a digestive enzyme that’s right for you based on your health concerns. Many will list the condition for which they are most suited on their bottle. Since you’re unsure, ask for guidance from your healthcare provider.

FAQs Related To Digestive Enzymes 

What’s the distinction between a digestive enzyme and a probiotic?

Probiotics are a kind of pill that contains helpful bacteria that can help to enhance gut flora. It contains helpful bacteria that can help to healthy gut bacteria. In contrast, digestive enzymes are exogenous enzymes that aid in digesting proteins, lipids, carbs, and fiber contained in diets.

In contrast, digestive enzymes are exogenous enzymes that aid in digesting proteins, lipids, carbs, and fiber contained in diets. Probiotics are recommended by certain doctors, like Orville Kolterman, MD, Chief Medical Officer at Pendulum. “A few people that believe that they need to have a digestive enzyme because they have frequent stomach aches or other GI issues would benefit from a probiotic,” he says.

Because they have frequent stomach aches or other GI issues would benefit from a probiotic,” he says. Probiotics have been demonstrated to assist the body break down proteins and restoring normal digestive function by replenishing and re-establishing bacteria in the gut. Always look for clinically established remedies and consult a medical practitioner before taking a probiotic or digestive enzyme.”

What’s the variation in prescribed digestive enzymes and over-the-counter enzymes like Pancreatic Enzymes?

Over-the-counter digestive enzymes can help people boost their metabolism, reduce bloating, and minimize the harmful effects of hard-to-digest foods like dairy and beans.

People with pancreatic insufficiencies, such as pancreatitis or cystic fibrosis, are given digestive enzymes on prescription.

Do digestive enzymes improve digestion?

Supplementing enzymes in clients with functional dyspepsia with indications that may help the digestive process has been recommended in studies. Digestive enzymes may help alleviate symptoms linked with nutrients that aren’t digested or absorbed properly.

This research also implies that many digestive enzyme supplements improves digestive enzymes’ normal functions throughout the stomach phase of food digestion.

Who should buy digestive enzymes?

Digestive enzymes are intended specifically for persons who suffer from gastrointestinal issues such as indigestion, bloating, and gas. They, together with probiotics and prebiotics, play a significant role in determining the overall digestive health of your digestive tract. To this purpose, most digestive enzymes may be beneficial if you experience gastrointestinal issues after eating, especially if they occur after meals that are particularly high in one macronutrient.

Digestive enzymes can also be helpful supplements if you’re taking a probiotic to boost the digestive health of your small intestine since the two can work together to help your body process food more efficiently. Most research on digestive enzyme supplements has focused on persons with specific medical problems, such as irritable bowel syndrome, who appear to benefit from increased digestive enzyme levels.

Digestion enzymes may be advantageous when on a restricted diet, even if they do not immediately lead to weight loss, because dysregulated digestion and gastrointestinal health have been linked to obesity.

Does digestive enzyme supplementation work?

According to the most recent studies, digestive enzymes lower gastrointestinal symptoms than a placebo. The only problem is that you should take a digestive enzyme supplement every day to get this effect, and it can take up to a month for the advantages to become noticeable.

Still, digestive enzyme supplements appear to be an effective and useful approach to relieve indigestion, bloating, and other gastrointestinal problems for something that is quite safe and simple to use.

Can digestive enzymes help with weight loss?

While there is no direct evidence that a digestive enzyme would cause weight reduction on its own, there does appear to be a link between digestive enzymes and probiotic bacteria, which have been linked to inducing or inhibiting weight loss.

When it comes to digestive enzymes, how long do they take to act?

Digestive enzymes should begin acting within five to ten minutes of eating a single meal. Your body does not need to absorb natural enzymes; they’re ready to break down proteins as soon as the capsule pops open, which should only take a few minutes with a high-quality digestive enzyme supplement.

On the other hand, natural digestive enzymes can take up to 30 days to start working and relieve symptoms of indigestion and other gastrointestinal disease or health condition.

Improvements in indigestion symptoms compared to placebo did not become statistically significant until at least 30 days into a clinical trial released in 2018, which proved the benefit of multi-ingredient digestive enzyme supplements on symptoms of indigestion.

Conclusion: Which Is The Most Effective Digestive Enzymes? 

These digestive enzyme supplements may help you if you have gas, bloating, or indigestion after every meal. The symptoms, on the other hand, vary from person to person. To avoid any issues, consult a doctor before using these supplements.

Despite the numerous advantages of these supplements, research has yielded mixed outcomes. As a result, proceed with caution. It may require searching to determine the best digestive enzyme supplement for you, but it will be worthwhile.

These tiny but mighty proteins for easier digestion in ways that no other supplement can. The majority of natural digestive enzymes are available in pill form. However, they are also available in gummy and droplet form. These options could be best for you if you don’t need to take whole pills.

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